Mandible / maxilla – Malignant tumors: ameloblastic fibrosarcoma. A case of an ameloblastic fibrosarcoma in the mandible is described. The primary tumor was seen in a 5-year-old child. In spite of repeated surgical. Introduction. Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumor. It can arise de novo, however one-third of cases may arise from a recurrent.

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A biopsy of the mass was performed. Received Jan 11; Accepted Mar 2. Only 2 cases of metastasis have been reported [ 1516 ].

Dentists should be familiar with signs and symptoms of malignant tumors of the jaws, especially rare cases with unusual presentation. Amekoblastic Conflict of Interest: Case report and review of the literature. Journal of Cranio-Maxillo-Facial Surgery. Ameloblastic fibrosarcoma of the jaw: Accessed December 31st, In case of oral and maxillofacial pain and symptoms, dentists are usually the first healthcare practitioner people consult.

Case report and literature review. However, sometimes, it is seriously difficult to differentiate AFS, especially low-grade tumors from ameloblastic fibroma. Open in a separate window. Sarcomatous overgrowth in recurrent ameloblastic fibrosarcoma. The usual clinical presentation consists of a patient who complains of ffibro painful but occasionally painless facial mass with accompanying paresthesia or dysesthesia.


Journal List Case Rep Pathol v. AFS is amrloblastic highly recurrent lesion. National Center for Biotechnology InformationU. Pathology Research and Practice.

Ameloblastic fibrosarcoma: a rare malignant odontogenic tumor.

J Oral Pathol Med. Histopathological examination revealed a biphasic tumor composed of inconspicuous islands of benign odontogenic epithelium and an abundant malignant mesenchymal component with marked cellularity, nuclear pleomorphism, hyperchromatism, and moderate mitotic figures with clear margins; one year after the surgical procedure, the patient is clinically and radiologically disease-free.

sarcomx The mesenchymal component consists of plump and spindle stromal cells which show mild to moderate cytologic atypia and numerous mitotic figures [ 11 ]. Ameloblastic fibrosarcoma, maxilla, odontogenic tumor. Panoramic radiograph showing area of mandibular resection with no evidence of recurrence 1 year after surgery. Malignant odontogenic tumors are classified as odontogenic carcinomas and odontogenic sarcomas [ 1 ]. The clinical, radiographic, and histopathological features were described in addition to the patient’s management and present status.

Consent Written informed consent was obtained from the patient for publication of this case report and the accompanying images.

As expected, the pain persisted and healing of the extraction site was not normal. Extraoral evaluation revealed a gross swelling over the left mandible Figure 1. Assessment of growth potential by MIB-1 immunohistochemistry in ameloblastic fibroma and related lesions of the jaws compared with ameloblastic fibrosarcoma.


Ameloblastic Fibrosarcoma of the Mandible: A Case Report and Brief Review of the Literature

AFS was first reported by Heath in describing it as a spindle cell sarcoma that also had epithelial cells resembling the cells of the enamel organ sarfoma 5 ]. Our patient presented an AFS in the posterior mandible. In this article, we reported a case of maxillary AFS. To the best of our knowledge, less than documented cases have been reported in the English sarcoka literature [ 6 ]. Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: Considering additional 9 cases reported so far,[ 23456891011 ] no vibro alteration was observed in age and gender distribution [ Figure 5 ] or location prevalence the mandible to maxilla ratio: Restricted molecular abnormalities of certain genes to the malignant transformation.